Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam

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Which cardiac issue is commonly associated with chronic iron overload?

Arrhythmia

Myocardial infarction

Cardiomyopathy

Chronic iron overload is often a consequence of frequent blood transfusions or certain conditions such as hereditary hemochromatosis. Over time, excess iron deposits in various organs, particularly the heart, leading to serious complications.

Cardiomyopathy, specifically dilated cardiomyopathy, is one of the primary cardiac issues associated with chronic iron overload. The iron deposits can lead to fibrosis and damage to the cardiac muscle, impairing the heart's ability to pump effectively. This condition can manifest as heart failure due to the structural and functional alterations in the myocardium caused by the accumulated iron.

Other cardiac issues can occur with chronic iron overload, but cardiomyopathy is distinctly linked to the detrimental effects of excess iron on heart muscle tissue, making it a key concern in the management of patients with chronic iron overload conditions.

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Congestive heart failure

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