Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam

Fava beans are specifically known to be associated with acute hemolysis in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. This condition results in a reduced sensitivity to oxidative stress due to a deficiency in the G6PD enzyme, which plays a crucial role in protecting red blood cells from damage. When a person with G6PD deficiency consumes fava beans, the natural compounds and oxidants present in these legumes can trigger oxidative stress, leading to the destruction of red blood cells, known as hemolysis.

This is a critical consideration for patients with G6PD deficiency, as the effects can manifest swiftly after ingestion. While lentils, spinach, and broccoli have their own nutritional profiles, they do not share the same potential for causing hemolysis in this patient population. Thus, it's essential for caregivers and healthcare providers to educate patients with G6PD deficiency about avoiding fava beans to prevent complications associated with this condition.