Certified Pediatric Hematology Oncology Nurse (CPHON) Practice Exam

DKC, or Dyskeratosis Congenita, is a rare inherited condition characterized by distinct clinical features including skin changes like hyperpigmentation. The hyperpigmentation associated with DKC is most commonly found on areas that have a significant amount of sun exposure, such as the face, neck, shoulders, and trunk. These regions are typically more affected because they receive more ultraviolet radiation, which can trigger the abnormal skin changes observed in DKC.

In addition to the hyperpigmentation, patients may also exhibit other skin manifestations, including poikiloderma, which presents with a combination of pigmentation changes. Because these areas of the body are more visible and subjected to environmental factors, it is logical for hyperpigmentation to be more pronounced in these locations, making this choice the best representation of common findings in DKC.

Other areas mentioned in the alternatives, such as the hands, feet, abdomen, and thighs, may have different patterns of pigmentation but are not typically the primary sites for the hyperpigmentation seen in dyskeratosis congenita.